8/25/2018

Cycle Update 2

I don't do this often, but if you read regularly, would you consider leaving a comment on this post? I appreciate each comment, especially right now when I'm "in the thick of it" with this cycle. Thank you!

Sooo, three days until my lining check on the 28th! Time continues to creeep by, but our first of two trips to Sacramento is now right around the corner. Since my last post, I have lowered my daily lupron dose from 10 to 5 units and have begun my estrogen patches, changing them out every other day. Those that have done the patches know they leave a lovely trail of gummy outlines across your torso that only come off when I scrape them with my fingernails (rubbing alcohol was ineffective, but if anyone knows how to easily remove these, let me know!).

I investigated and decided I'm going to do an acupuncture treatment the day before transfer to help with blood flow to the uterus. There is some research to support this. Acupuncture has not been an enjoyable activity for me in the past, so I debated some on this decision. In the end, several people on my Cal IVF FB page felt it was helpful, the research seemed to specifically support receiving a treatment within 24 hours prior to transfer, and I decided to visit RC's acupuncturist here in town before we drive over to Sac. He said she does Japanese-style acupuncture with thinner needles, so fingers crossed.

We have continued our lively discussions about whether to transfer one or two. It seems that an individual's risk tolerance represents a huge factor in their opinion of what we should do. My brother has a very low tolerance for risk, and he had a conniption fit when I mentioned we're considering transferring two. The nurses at the clinic also seem clear in their opinion that they would recommend one. Several other people we have asked say something to the effect of, "You're putting so much into it, you should transfer two and get more bang for your buck." RC and I are currently in a two-day experimental period during which we are mentally choosing to transfer one and seeing how it feels and what comes up.

This experiment has already borne fruit in the form of inspiration to look up the specific statistics on the increased risk of preeclampsia, diabetes, and pre-term birth. After reviewing some reputable studies and websites yesterday, my current understanding and belief is that, while there is an increased risk of these issues surfacing, especially preeclampsia, if the 45-year-old+ embryo recipient is generally healthy (blood pressure, weight etc.) prior to transfer and is monitored frequently, the overall outcomes are positive and don't differ significantly from singleton pregnancies. I don't know why I didn't look up the specific details and statistics earlier, but I think maybe I was protecting my desire to transfer two. When we undertook this two-day experiment of planning to transfer one, it opened up willingness to investigate these issues further. In any case, I'm glad I did it and it yielded some useful information.

When I (finally!) had my first local obgyn appointment yesterday, she was very nice and encouraging but didn't have a clear opinion on the one versus two question. She just brought up pros and cons on either side. Same scenario when RC asked his friend and chiropractor. Both said it's not a question with a clear answer, and we need to discuss and decide as a couple. I guess they're right, and we are trying, but we are not there quite yet. Being established with a local doctor feels great, though, and at least I can get local orders for tests and monitoring now.

One more aspect I want to share about this two versus one decision... for many people, it would be a no-brainer: 70% chance of success with one vs. 80-85% with two, plus a 50% chance of twins if you transfer two? Transfer one of course! But when you have gone through many years of trying and failing, including 7 IUIs, which each had maybe a 10-15% of working tops,  10-15% is not a negligible number. 80-85% sounds a LOT better to me, and I would MUCH rather have twins and take all the risks that go along with them than have NO BABY. So yeah, I acknowledge that I bring some history to the table on this decision. What would you do if you were me?

Lastly, I hoped we would hear from the clinic yesterday about our donor's follicle count, but my nurse there said it will be next week. I'm dying to know! She did tell us that her baseline and all initial tests came back with no problems, and she received and started the medications. I have been thinking of her and sending positive energy, and a few days ago I went on Ets-y and found a cool Celtic gratitude necklace/pendant to give her in appreciation. We share Celtic/Irish heritage (along with English and French), so I thought that was meaningful.

I'll post again after the lining check; hopefully with good news!

8/09/2018

Cycle Updates

I wanted to write an update on our donor egg IVF cycle, which officially started with medication two days ago (!).

Once we paid the (huge) fee for the procedure, we started getting excited and having many conversations about whether we wanted to transfer one or two embryos. The percentage of success with one embryo is 70% and with two, 80%. Apparently, to most people, 10% seems negligible, but that does not reflect my feelings. Maybe it's my teaching background - the difference between a C and a B - or maybe it's the psychological impact that 8 out of 10 or 80% has on my brain (I want those odds!), but it seems fairly significant to me.

But a 50% chance of twins if we transfer two? Those are significant odds, as well. We are open to twins and would much prefer them to a failed cycle, but we would definitely rather have one than two. Of course, two would be much harder on my (older mom) body and there are increased chances of preeclampsia and pre-term birth, moreso the latter I think.

We also think, however, about using donor egg and how this might increase the desire and benefit for a child to have a sibling. RC was a twin and has positive feelings about that. Twins could be lots of fun, right?! But also expensive and lots - and lots and lots - of work! So, we are continuing to reflect on this and feel into whether at some level we want or would be happy about having twins, which I feel would be a necessary precursor to transferring two.

In terms of concrete actions, I started Lupron day before yesterday. I've administered Lupron subcutaneously to myself before, so it is not too daunting and, strangely, a little bit fun. I just love the feeling of moving forward and each injection contributing to the success of this cycle. Today was my last BCP, so that feels momentous, as well. Hopefully, it's the last pack of pills for the next nine months and maybe ever!

Forthcoming exciting action steps include starting my Estradiol patches on the 14th, then going to Cal IVF for my lining check appointment on the 28th. We know the area a little better now, so rather than booking a hotel close to downtown and some very sketchy areas, we booked a Marriott within walking distance of the clinic. I love staying in (decent) hotels, it's like a fun introvert slumber party for me. They serve warm breakfast in the morning, too - yum.

If all goes well, the donor will donate the eggs on September 2nd, and somewhere around this time, I start dreaded progesterone injections. I have gotten a few helpful tips from friends; if you have any advice on how to make it less intimidating or painful, I would love to hear them. Then, the embryo(s) will be transferred to my uterus around the 7th. I'm so excited. :) Please send us good thoughts!